Selective Oxidation of Polyfunctional 2-Amino-1,3-propanediol Derivatives
分类信息 - Paper认证
| 姓名 |
Guojian Lu |
| 所在学校或单位 |
Wuhan |
| 文章题目 |
Selective Oxidation of Polyfunctional 2-Amino-1,3-propanediol Derivatives |
| 期刊名 |
J. Org. Chem |
| 年份，卷（期），起止页码 |
2004, 69, 10, 3593-3594 |
| 影响因子 |
3.790 |
| 文章链接 |
http://dx.doi.org/10.1021/jo049973y |
Oxidation of polyfunctional threo-(1S,2S)-2-amino-1,3-propanediol derivatives with a 717 anion-exchange resin-supported bromine has been investigated. The result showed that oxidized products were in close relationship with the substituents at nitrogen in the starting materials. Its primary and secondary amine derivatives were oxidized in the presence of Na2HPO4 to give essentially a substituted chiral oxazoline or C(3)-O acylated product in high yield, while oxidation of its N,N-dimethyl derivative mainly gave a chiral N-methyl oxidation-formylation product. This selective oxidation was first observed in 2-amino-1,3-propanediol chemistry
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Selective Oxidation Polyfunctional propanediol Derivatives
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